Minerals and heavy metals in Labisia pumila var. alata folia of Selected Geographic Origins

Main Article Content

Ade Chandra Iwansyah
Noorazizah Zainal Abidin
Mashitah Mohammad Yusoff


Labisia pumila var. alata leaves (LP) with a long history of use folk remedy and endemic to the Malay Archipelago, is now supplied worldwide as ingredient of functional foods and beverages. Minerals and heavy metal concentrations in Labisia pumila var. alata folium (LP) of selected geographic origin based on microwave-assisted sample digestion and inductively coupled plasma mass spectrometry (ICP-MS) were determined.  Fifteen elements comprising minerals (Ba, Ca, Cr, Co, Cu, Fe, K, Mg, Na, Ni, Rb and Zn) and heavy metals (As, Cd and Pb) were analyzed with an inductively coupled plasma – mass spectrometer (ICP-MS). The highest nutrient concentration was measured in LP from Tilu Mountain (Cu, Na, K, Mg and Zn). The highest values of Ba, Ca, Co, Cr and Fe were detected in LP from Raub. Ni and Rb were highest in LP from Cibeundey Village. As was highest in LP from Raub (0.04 ± 0.00 mg/kg). The highest Pb contents were in LP from Tilu Mountain (2.90 ± 0.10 mg/kg) and LP from Halimunan-Salak Mountain (3.12 ± 0.03 mg/kg), all of which were well within the permissible limits as specified by the U.S. FDA for edible plant parts.


Article Details

How to Cite
Iwansyah, A., Abidin, N., & Yusoff, M. (2019). Minerals and heavy metals in Labisia pumila var. alata folia of Selected Geographic Origins. Jurnal Kartika Kimia, 2(1), 1-6. https://doi.org/10.26874/jkk.v2i1.25


[1] W. Jia and L. Zhang, “Challenges and Opportunities in the Chinese Herbal Drug Industry,” in Natural Products: Drug discovery and therapeutic medicine, Zhang, L., New Yoirk: Springer, 2005, pp. 229–250.
[2] J. T. Dwyer et al., “Progress in developing analytical and label-based dietary supplement databases at the NIH Office of Dietary Supplements,” J. Food Compos. Anal., vol. 21, no. 1, pp. S83–S93, 2008.
[3] P. Kalny, Z. Fijałek, A. Daszczuk, and P. Ostapczuk, “Determination of selected microelements in polish herbs and their infusions,” Sci. Total Environ., vol. 381, no. 1–3, pp. 99–104, 2007.
[4] World Health Organization, Food nutritional quality: Micronutrients: Recommended nutrient intakes. World Food Programme, 2002.
[5] S. Millour, L. Noël, A. Kadar, R. Chekri, C. Vastel, and T. Guérin, “Simultaneous analysis of 21 elements in foodstuffs by ICP-MS after closed-vessel microwave digestion: Method validation,” J. Food Compos. Anal., vol. 24, no. 1, pp. 111–120, 2011.
[6] I. H. Burkill, A dictionary of the economic products of the Malay Peninsula, Vol. II. London: Crown Agents for the Colonies, 1935.
[7] M. Fazliana, H. F. Gu, C.-G. Östenson, M. M. Yusoff, and W. M. Wan Nazaimoon, “Labisia pumila extract down-regulates hydroxysteroid (11-beta) dehydrogenase 1 expression and corticosterone levels in ovariectomized rats,” J. Nat. Med., vol. 66, no. 2, pp. 257–264, 2011.
[8] R. Chizzola and C. H. France, “Metallic trace elements in medicinal and aromatic plants from Austria,” J. Appl. Biol., vol. 70, no. 1, pp. 52–56, 1996.
[9] I. Lavilla, A. V Filgueiras, and C. Bendicho, “Comparison of Digestion Methods for Determination of Trace and Minor Metals in Plant Samples,” J. Agric. Food Chem., vol. 47, no. 12, pp. 5072–5077, 1999.
[10] R. Murray, V. Rodwell, D. Bender, and K. M. Botham, Harper’s Illustrated Biochemistry, 28th Editi. New York: McGraw-Hill Medical, 2009.
[11] I. Kaya and N. İncekara, “Contents of some wild plants species consumed as food in Aegean region,” J. Turkish Weed Sci., vol. 3, pp. 56–64, 2000.
[12] D. A. Eastmond, J. T. MacGregor, and R. S. Slesinski, “Trivalent Chromium: Assessing the Genotoxic Risk of an Essential Trace Element and Widely Used Human and Animal Nutritional Supplement,” Crit. Rev. Toxicol., vol. 38, no. 3, pp. 173–190, 2008.
[13] P. R. Pehrsson, D. B. Haytowitz, and J. M. Holden, “The USDA’s National Food and Nutrient Analysis Program: update 2002,” J. Food Compos. Anal., vol. 16, no. 3, pp. 331–341, 2003.
[14] M. J. McLaughlin, D. R. Parker, and J. M. Clarke, “Metals and micronutrients – food safety issues,” F. Crop. Res., vol. 60, no. 1–2, pp. 143–163, 1999.
Abstract viewed = 248 times
PDF downloaded = 140 times